Soyuz TMA-5 was a Soyuz mission to the International Space Station (ISS) launched by a Soyuz-FG launch vehicle.

25th manned flight to ISS.

Soyuz TMA-5 is a Soyuz spacecraft that was launched on October 14, 2004 by a Soyuz-FG rocket from Baikonur.
The Expedition 10 crew, Leroy Chiao of the U.S.A. and Salizhan Sharipov of Russia replaced the Expedition-9crew, Gennady Padalka - Cdr. Russia and Edward Fincke U.S.A.
The launch of Expedition 10 was delayed beyond its scheduled October 9, 2004 launch date. During preflight testing, an explosive blot was accidentally activated on the Soyuz TMA-5 spacecraft. The resulting damage was repaired prior to launch.
The docking maneuver had to be done manually, as the approach by the automatic system was too fast.
The undocking was done manually as well, as a cautionary measure to save power on a faulty battery.
After 193 days in the station the Expedition 10 crew returned to a soft landing in Kazakhstan together with Italian RobertoVittori who had flown up with the Expedition 11 crew on Soyuz TMA-6.

The mission carried out the ISS Expedition 10. They were called a "caretaker" crew. Following a two-day solo flight Soyuz TMA-5 docked to ISS on October 16, 2004. Salizhan Sharipov and Leroy Chiao replaced the Expedition 9 crew.

17 experiments from the NASA were planned, including the first work with the DAFT experiment and completing the ISSI. This experiment was conducted during Space Station Expedition 7 and/or Expedition 8.

Notable accomplishments included replacing critical hardware in the Quest Joint Airlock; repairing U.S. spacesuits; and submitting a scientific research paper on ultrasound use in space. Leroy Chiao was also the first astronaut to vote in a U.S. Presidential election from space.

Progress M-51 was launched at 22:19:34 UTC on December 23, 2004. The spacecraft docked with the Aft port of the Zvezda module at 23:57:45 UTC on December 25, 2004. Progress M-51 carried supplies to the International Space Station, including food, water and oxygen for the crew and equipment for conducting scientific research. The freighter remained docked for two months before undocking at 16:06:30 UTC on February 27, 2005 to make way for Progress M-52. Between undocking and deorbit, Progress M-51 was used for a series of tests. It was deorbited at 16:17:00 UTC on March 09, 2005. The spacecraft burned up in the atmosphere over the Pacific Ocean, with any remaining debris landing in the ocean at around 17:03:11 UTC.

The first EVA by Leroy Chiao and Salizhan Sharipov was performed on January 26, 2005 (5h 28m) to install a work platform on the hull of the command module, to mount the European commercial experiment Rokviss, to relocate the Japanese space exposure experiment package and to install a Russian biological experiment.

Progress M-52 was launched at 19:09:18 UTC on February 28, 2005. The spacecraft docked with the Aft port of the Zvezda module at 20:10:08 UTC on March 02, 2005. Progress M-52 carried supplies to the International Space Station, including food, water and oxygen for the crew and equipment for conducting scientific research. It also carried the TNS-0 nanosatellite, which was deployed from the ISS on March 28, 2005 at 08:30 UTC. The freighter remained docked for three and a half months before undocking at 20:16:10 UTC on June 15, 2005 to make way for Progress M-53. It was deorbited at 23:16:00 UTC on June 15, 2005. The spacecraft burned up in the atmosphere over the Pacific Ocean, with any remaining debris landing in the ocean at around 00:02:41 UTC on June 16, 2005.