Soyuz T-4 May 12, 1981 - Landing May 26th 1981 - Docking with Salyut 6 delayed after the onboard Argon computer determined it would occur outside of radio range with the TsUP. In mid-May, Kovalyonok and Savinykh replaced the Soyuz-T 4 probe with a Salyut drogue. This may have been an experiment to see if a Soyuz-T docked to a space station could act as a rescue vehicle in the event that an approaching Soyuz-T equipped with a probe experienced docking difficulties and could not return to Earth.

The docking with Salyut 6 was delayed after the Soyuz's onboard Argon computer determined it would occur outside radio range with the TsUP. Despite this, the docking occurred successfully on 13 March 1981. The Progress 12 spacecraft was already docked to the station by the time the crew arrived, and they spent several days unloading the Progress before its undocking on 19 March. This freed the remaining docking port for the arrival of the Soyuz 39/EP-9 crew on 22 March.

In mid-May, Kovalyonok and Savinykh replaced the spacecraft's probe with a Salyut drogue. This may have been an experiment to see if a Soyuz-T docked to a space station could act as a rescue vehicle in the event that an approaching Soyuz-T equipped with a probe experienced docking difficulties and could not return to Earth.

The EO-6 crew undocked from Salyut 6 on 26 May, leaving behind the Soyuz's orbital module. Soyuz T-4 landed over three hours later, touching down 125 kilometres (78 mi) east of Dzhezkazgan, Kazakh SSR